Publications
Below is a list of selected scientific publications arising from our laboratory. Click on either David Long, Paul Winyard or Rukshana Shroff for more!
We found that treating mice with a protein called thymosin beta 4 by gene therapy protects podocytes in a model of glomerular injury by protection of the podocyte cytoskeleton.
We found that addition of lithium encourages the production of nephrons from human embryonic kidney cells
We found that a protein that is normally involved in instructing cells how to orientate themselves, called Vangl2, is has a role in protecting podocytes in the kidney from damage in renal disease in mice
We used 3D imaging techniques and computerised analysis to find out how lymphatics grow during normal kidney development and what goes wrong in polycystic kidney disease
We found that VEGF-C, a protein which normally helps blood vessels and lymphatics to grow, helps to reduce the severity of disease and improve renal function in mouse models of polycystic kidney disease
We identified a new kind of kidney disease in humans which occurs due to faulty modifications to messengers of the cell: RNA